LAB REPORT ( DISEASE REPORT) i put the file look the instruction there.
use this source to look up info about it from this
https://www.nclive.org/https://www.nclive.org/
Lyme Disease ( borrelia Burgdorferi)
Date: 2010
From: World of Health
Publisher: Gale
Document Type: Disease/Disorder overview
Length: 655 words
Content Level: (Level 5)
Lexile Measure: 1360L
Full Text:
Though it has probably been in existence for a long time, Lyme disease was only recently identified as a distinct illness. The disease is caused by the spirochete Borrelia burgdorferi, a corkscrew-shaped microorganism, which is spread by ticks that thrive in wooded areas and tall grasses and infect deer, mice, and domestic animals as well as humans. Most common in the United States areas of New England, the upper Midwest, and northern California, it has been diagnosed in more than 40 states. Although Lyme disease is not fatal, it can cause lasting debilitation.
A Lyme disease infection progresses through three stages. The first stage includes a bull’s-eye-like rash that can appear at the site of the tick bite in a few days to a few weeks. There can also be symptoms similar to influenza, headaches, and soreness in the neck. The second stage includes irregular heartbeat, joint pains, disturbances of vision and memory, and facial nerve paralysis. The disease can then progress to a third stage that includes joint inflammation and arthritis. While it can be easily treated with antibiotics, especially oral tetracycline, in the early stages, Lyme disease is often misdiagnosed until it has progressed to the second or third stage, during which the damage can become permanent. Antibiotics are also being developed for chronic Lyme disease which is characterized by chronic or intermittent symptoms.
The disease was first reported in Lyme, Connecticut, in 1974 by American rheumatologist Allen Steere (1943-), who noticed that certain patients were exhibiting a distinct set of symptoms that could not be attributed to other known illnesses. Symptoms resembling those of Lyme disease had been reported in parts of Europe since the turn of the century, but clinicians were not sure whether the European syndrome had a similar origin to Lyme disease.
Then, in 1981, a survey of microorganisms in ticks revealed that a tick-borne spirochete was responsible for both the European and American syndromes. Because many people in the United States and Europe contract the disease without apparent exposure to the tick, many experts believe that mosquitoes, biting flies, and birds may also spread the organism.
Despite a full understanding of the disease, researchers have been developing a vaccine. At Yale University, scientists isolated the gene in the Lyme disease spirochete that leads to the production of the protein OspA, a protein common to many bacteria. Using genetic engineering, the researchers induced another bacterium to produce large quantities of OspA. When they injected laboratory mice with the protein and exposed the mice to the Lyme disease organism, none of them developed the disease. Furthermore, antibodies could be extracted from the mice and injected into uninfected mice, affording them protection from the disease as well.
While vaccines are undergoing testing in humans, scientists have recently discovered the DNA (deoxyribonucleic acid) sequence for the causative agent, Borrelia burgdorferi. This advance will help researchers develop new diagnostic tests and vaccines, as well as determine individual susceptibility to chronic symptoms. Until then, education and proper early diagnosis appear to be the best means to control the disease. Experts advise campers and hikers to cover exposed skin, especially on the legs, when walking in the woods or tall grasses. People should also check themselves and their children thoroughly for ticks (particularly deer ticks roughly the size of a pinhead), and gently remove any ticks they find with tweezers to insure that the mouthparts of the tick are not left in the bite. Because the Lyme disease spirochete resides in the midguts of ticks, crushing the ticks could inject the contents of the midgut into the bite wound.
According to the National Institute of Allergy and Infectious Diseases, the annual incidence of Lyme disease is about 100,000 people, which is approximately 0.04% of the population. In 2008, 28,921 cases of Lyme disease were reported to the U.S. Centers for Disease Control and Prevention (CDC), along with 6,277 probable cases.
Full Text: COPYRIGHT Gale, a Cengage Company
Source Citation (MLA 9th Edition)
“Lyme Disease.” World of Health, Gale, 2010. Gale In Context: Biography, link.gale.com/apps/doc/CV2191500793/BIC?u=nclivecvcc&sid=bookmark-BIC&xid=4d3c95e8. Accessed 20 Feb. 2023.
Gale Document Number: GALE|CV2191500793
and heres the citings
Cheyne, K., Lynn, G. E., Pedra Joao, H. F., Utpal, P., Sukanya, N., & Erol, F. (2020). Interactions between 0RW1S34RfeSDcfkexd09rT2borrelia burgdorferi1RW1S34RfeSDcfkexd09rT2 and ticks. Nature Reviews.Microbiology, 18(10), 587-600. doi:https://doi.org/10.1038/s41579-020-0400-5Cheyne, K., Lynn, G. E., Pedra Joao, H. F., Utpal, P., Sukanya, N., & Erol, F. (2020). Interactions between 0RW1S34RfeSDcfkexd09rT2borrelia burgdorferi1RW1S34RfeSDcfkexd09rT2 and ticks. Nature Reviews.Microbiology, 18(10), 587-600. doi:https://doi.org/10.1038/s41579-020-0400-5Cheyne, K., Lynn, G. E., Pedra Joao, H. F., Utpal, P., Sukanya, N., & Erol, F. (2020). Interactions between 0RW1S34RfeSDcfkexd09rT2borrelia burgdorferi1RW1S34RfeSDcfkexd09rT2 and ticks. Nature Reviews.Microbiology, 18(10), 587-600. doi:https://doi.org/10.1038/s41579-020-0400-5
Stark, J. H., Li, X., Zhang, J. C., Burn, L., Valluri, S. R., Liang, J., . . . Gessner, B. D. (2022). Systematic review and meta-analysis of lyme disease data and seropositivity for 0RW1S34RfeSDcfkexd09rT2borrelia burgdorferi1RW1S34RfeSDcfkexd09rT2, china, 2005‒2020. Emerging Infectious Diseases, 28(12) doi:https://doi.org/10.3201/eid2812.212612Stark, J. H., Li, X., Zhang, J. C., Burn, L., Valluri, S. R., Liang, J., . . . Gessner, B. D. (2022). Systematic review and meta-analysis of lyme disease data and seropositivity for 0RW1S34RfeSDcfkexd09rT2borrelia burgdorferi1RW1S34RfeSDcfkexd09rT2, china, 2005‒2020. Emerging Infectious Diseases, 28(12) doi:https://doi.org/10.3201/eid2812.212612Stark, J. H., Li, X., Zhang, J. C., Burn, L., Valluri, S. R., Liang, J., . . . Gessner, B. D. (2022). Systematic review and meta-analysis of lyme disease data and seropositivity for 0RW1S34RfeSDcfkexd09rT2borrelia burgdorferi1RW1S34RfeSDcfkexd09rT2, china, 2005‒2020. Emerging Infectious Diseases, 28(12) doi:https://doi.org/10.3201/eid2812.212612Stark, J. H., Li, X., Zhang, J. C., Burn, L., Valluri, S. R., Liang, J., . . . Gessner, B. D. (2022). Systematic review and meta-analysis of lyme disease data and seropositivity for 0RW1S34RfeSDcfkexd09rT2borrelia burgdorferi1RW1S34RfeSDcfkexd09rT2, china, 2005‒2020. Emerging Infectious Diseases, 28(12) doi:https://doi.org/10.3201/eid2812.212612
Schoen R. T. (2020). Lyme disease: diagnosis and treatment. Current opinion in rheumatology, 32(3), 247–254. https://doi.org/10.1097/BOR.0000000000000698Schoen R. T. (2020). Lyme disease: diagnosis and treatment. Current opinion in rheumatology, 32(3), 247–254. https://doi.org/10.1097/BOR.0000000000000698Schoen R. T. (2020). Lyme disease: diagnosis and treatment. Current opinion in rheumatology, 32(3), 247–254. https://doi.org/10.1097/BOR.0000000000000698Schoen R. T. (2020). Lyme disease: diagnosis and treatment. Current opinion in rheumatology, 32(3), 247–254. https://doi.org/10.1097/BOR.0000000000000698Schoen R. T. (2020). Lyme disease: diagnosis and treatment. Current opinion in rheumatology, 32(3), 247–254. https://doi.org/10.1097/BOR.0000000000000698
Item 1-1 of 1 (Display the 1 citation in PubMed)
1.
Lyme disease: diagnosis and treatment.
Schoen RT.
Curr Opin Rheumatol. 2020 May;32(3):247-254. doi: 10.1097/BOR.0000000000000698.
PMID: 32141956 Review.
Item 1-1 of 1 (Display the 1 citation in PubMed)
Klein, A. (2020). Lyme disease vaccine performs well in clinical trials. New Scientist, 247(3294), 13. https://doi-org.proxy032.nclive.org/10.1016/s0262-4079(20)31352-xKlein, A. (2020). Lyme disease vaccine performs well in clinical trials. New Scientist, 247(3294), 13. https://doi-org.proxy032.nclive.org/10.1016/s0262-4079(20)31352-xKlein, A. (2020). Lyme disease vaccine performs well in clinical trials. New Scientist, 247(3294), 13. https://doi-org.proxy032.nclive.org/10.1016/s0262-4079(20)31352-xKlein, A. (2020). Lyme disease vaccine performs well in clinical trials. New Scientist, 247(3294), 13. https://doi-org.proxy032.nclive.org/10.1016/s0262-4079(20)31352-xKlein, A. (2020). Lyme disease vaccine performs well in clinical trials. New Scientist, 247(3294), 13. https://doi-org.proxy032.nclive.org/10.1016/s0262-4079(20)31352-x
( also about the host) also mention justin bieber as one of the known famous person in united state that have Lyme disease.
use
