What are the most common side effects and adverse effects of opioids?

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1. An issue that can occur with long-term opioid use is tolerance. Explain drug tolerance; what is the result of drug tolerance?

2. What are the most common side effects and adverse effects of opioids?

3. What is the difference between drug dependence and drug addiction?

4. Why did the federal government file criminal charges against Purdue Pharma in 2007; what was the outcome of the case?
5. Click on the following links and answer the questions related to the October 2020 update on charges against Purdue Pharma:
https://www.justice.gov/opa/pr/justice-department-announces-global-resolution-criminal-and-civil-investigations-opioid

How much was the settlement that the Federal government reached with Purdue Pharma in October 2020?
How much did the Sackler family agree to pay?
What charges did the company agree to plead guilty to?

https://www.reuters.com/article/us-purdue-pharma-opioids-plea/oxycontin-maker-purdue-pharma-pleads-guilty-to-criminal-charges-idUSKBN2842SQ

To whom did Purdue pharma pay kickbacks?
How much money did the company make from the sale of OxyContin?
Since 1999, how many people in the United States have died from opioid-related overdoses?

6. Approximately how many people in America died from an opioid overdose in 2021? How does that number compare to deaths from opioid overdose in 2020? How did the COVID Pandemic affect the number of overdose deaths in 2020?

7. In April of 2018, what overdose-reversing drug did the US Surgeon General recommend that all Americans carry? Explain how the drug works (mechanism of action).

8. Discuss at least 3 ways that health care providers can aid in combating the opioid crisis in America.

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