Name of Microorganism: Yersinia Pestis 1. Desсrіption of the Microorganism (week 1) Write a paragraph describing your organism. Please be sure to include the type of organism (bacterial, viral, fungal, protozoa, helminth, etc), morphology (shape, arrangement , colony morphology if applicable), desсrіption of structure (gram result, type of nucleic acid or virion structure, spore type, etc if applicable) and also the type of microscope and/or stain you would use to view the organism. Please use proper scientific terminology and good grammar and sentence structure throughout this project. 2. Virulence Factors Include a paragraph on the virulence factors the pathogen has and how they affect the host. Please enhance this with detailed explanations of the virulence factors and how they affect the host as you gain a better understanding of them throughout the semester. 3. Immunity Which innate and/or adaptive defenses protect us from infection by this bacterium? Does this pathogen induce a specific type of immune response (example: delayed-type hypersensitivity)? If so, which one(s)? 4. Pathology (Infectious Disease Information) What condition(s) or infectious disease(s) does it cause? Which tissues or organs are affected, and how are they affected (for example, chronic TB is characterized by lung tubercles)? Describe the complications that can result if the infection is left untreated. Are these acute, chronic, or latent infections? What organ system(s) does it infect? Is it an opportunistic pathogen? If so, where is it normally found in the body? 5. Epidemiology Draw and label a diagram on how this organism is transmitted. Make sure you include the reservoirs of infection, any vectors if involved in transmission, the type of transmission, and portals of entry and exit. 6. Prevention Is there a childhood vaccine against this microbe? Name of vaccine If so, when is it administered (the recommended schedule, including boosters if recommended)? If the vaccine is not recommended during childhood, which at-risk group should get the vaccine, and when? Describe the type of vaccine and how it works : If there is no vaccine available, list at least three measures the can be implemented to prevent people from acquiring this infection. 7. Treatment Chemotherapeutic agents: antibiotic or antiviral etc. used to treat. Mechanism of action for these chemotherapeutic agents. Why is this agent efficacious against this particular organism ? Additional therapeutic agents or practices. If there is no treatment specific for your organism what measures are take? 8. Clinical relevance Are there any MDR (multi-drug resistant) strains of this microorganism? If so, name the strain(s) Is this strain a known healthcare-associated pathogen? Which persons/procedures within a clinical or healthcare-assisted setting are particularly at risk Which antibiotics are used against the multi-drug resistant strains?
