Clinical Case study:SAMPLE RESPONSE FOR CASE STUDY .

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Question 2 D and E -SAMPLE RESPONSE FOR CASE STUDY d.Detailed desсrіption of what type of mutations have been found for each gene within this tumor and possible ways this may affect or change cellular function SAMPLE RESPONSE: The only two mutations in the gene found in XXXXX cancer are XXX and OR missense/nonsense/frameshift mutations. When it is mutated, XXXX cannot be broken down when it is not needed, so it accumulates in the cell. It can move to the nucleus/cytoplasm and promotes unchecked proliferation of cells, allowing tumors to develop. E Role this gene plays in tumor phenotype and metastatic potential. SAMPLE RESPONSE: Mutated XXXX showed to have an inflammatory phenotype. It also promotes metastasis/does not promote metastasis

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