Review the Learning Resources focusing on learning and memory paying special attention to how brain cells change when learning takes place.
Choose ONE of these article options on the topic cellular basis of memory:
“The Role of Hippocampal Structural Synaptic Plasticity in Repetitive Transcranial Magnetic Stimulation to Improve Cognitive Function in Male SAMP8 Mice”
OR
“Long-Term DL-3-n-Butylphthalide Treatment Alleviates Cognitive Impairment Correlate With Improving Synaptic Plasticity in SAMP8 Mice”
OR
Changes in synaptic plasticity are associated with electroconvulsive shock-induced learning and memory impairment in rats with depression-like behavior”
OR
You may choose your own article; however, it must be approved by your instructor by Thursday before the assignment is due.
The Assignment (2–4 pages):
First, consider the cellular basis of long-term potentiation (LTP). Where in the brain does this occur and what happens? In your answer, include details of the neurotransmitters and receptors involved as well as what happens at the level of the receptor to enable LTP. Also, describe the changes that occur in both the presynaptic and post-synaptic cells as a result of LTP.
Summarize your article about the cellular basis of memory in enough detail that your reader will understand what was done in the study and what the results of the study were (similar to the articles you found in BioPsychology.com in the first week).
Evaluate how the findings might apply to a clinical setting, such as Alzheimer’s disease, anterograde or retrograde amnesia, or a condition such as post-traumatic stress disorder (PTSD).