Discuss on KatG and inhA mutations in M. Tuberculosis affecting resistance to antibiotic isoniazid

Discuss on KatG and inhA mutations in M. Tuberculosis affecting resistance to antibiotic isoniazid

Looking for literature review of KatG and inhA mutations in M. Tuberculosis and specifically how they affect the antibiotic isoniazid.

Structure:
– overview of mutation rates
– KatG and its mutations
– inhA and its mutations
– Testing for KatG and inhA mutations
– discussion/any comments

Thanks
Jana