Discuss a drug research based on abnormal neutrophilic responce in PSD.

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writing has to be in ACS style

Chapters in the review
1. Intro
2. Post-stroke depression link to Post-stroke anxiety
3. Post- stroke depression link to Post-stroke hyperlocomotor activity
4. Post stroke depression link to BBB injury
5. Pathogenesis
A. Role of monoamine system
B. Role of glutamatergic system
C. Role of Excitotoxicity
D. Role of Gut brain axis
E. Role of neuroinflamation
F. Role of abnormal neutrophilic responce
G. Role of HLA Dysregulation

6. Research on drugs
A. Research on drugs that are based on monoamin theory
1) SSRIs
2) SNRIs
3) NDRIs
4) MAOIs
5) TCAs
B. Glutamate based antidepressants
NMDA blockers
1) Ketamine
2) Memantine
3) Magnesium
4) D-cycloserine
AMPA antagonists
Antagonists mGluRs (Groups I,II,III)
Blood glutamate scavengers
1. Pyruvate
2. Oxaloacetate
C) Antiexcitotoxic drugs in PSD
D) Drug research on Gut brain axis in PSD
E) Drug research on Antiinflamative mechanism in PSD
F) Drug research based on abnormal neutrophilic responce in PSD
G) drugs based on of HLA Dysregulation

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