Interstitial Cystitis

Words: 402
Pages: 2
Subject: Uncategorized

Interstitial cystitis (IC) is a bladder pain syndrome that has no distinct cause or course of treatment. The disorder is generally characterized by bladder pain during micturition, a constant feeling of having to void the bladder, and increased frequency of micturition. It is somewhat uncommon, with an estimated incidence of 1 in 20,000, primarily affecting women; however, there are estimates that around 10% of women may exhibit at least some symptoms of IC.

Experts even disagree on standard diagnostic criteria. Aside from the afore-mentioned symptoms, it has been suggested that glomerulations (spots of hemorrhage in the lining of the bladder), a commonly used criterion for diagnosing IC, has no valid scientific basis since these may be found in the bladders of many individuals without any symptoms of IC whatsoever. There are a few recent findings, however, that indicate individuals with IC exhibit specific autonomic imbalances, a modified central pain response, and changes in the anatomy of the bladder mucosa that disrupt epithelial function and amplify pain signals.

In your response, describe in more detail the 3 general changes in patients with IC, and elaborate on how these changes may result in an amplification of pain and in the general bladder voiding urgency sensations that IC patients endure. Also, what are the most common therapeutic approaches to treating IC patients, and how successful have these approaches been in treating the symptoms of IC?

In addition to your original response, you will need to respond to at least two other students’ original posts. Responses should be substantive in nature instead of just reiterating what the original poster stated, or a “good job explaining” or “me too” type of post.

Please note that in your response, plagiarism is not allowed. Please do NOT simply cut and paste information from books, journals, websites, or other sources. In addition, direct quotation of sources, regardless of whether or not the source is cited, is not allowed. Please summarize the material and what you have learned in your own words.

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