Introduction and Definition of Drug interaction Epidemiology of Drug interaction Types of Drug interaction: 1- drug-drug interaction Concept of drug-drug interaction including the following: CYP P450 ISOENZYMS INTERACTION P.GLYCOPROTEIN BCRP/ABCG2 DRUG DISPLACEMENT-PROTEIN BINDING 2- Drug -Food interaction Concept Major interaction with adding a table 3- Drug – Disease interaction Concept Discuss the role of pharmacist/clinical pharmacists in identifying and resolving drug interaction with health care professionals and with patients as well.