Explain why nitroglycerine is usually not given orally and why different routes of administration are utilized.

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Prompt for Discussion:Explain why nitroglycerine is usually not given orally and why different routes of administration are utilized. What effect do the different routes of administration have on the bioavailability of the drug. Description of discussion Discussion: Impact of Pharmacokinetics on Medication Selection and Administration As an advanced practice nurse, you will likely be responsible for selecting and prescribing pharmaceuticals to address your patients’ health needs and concerns. To what extent is understanding the pharmacokinetics of a certain medication important in your decision-making process when prescribing a medication for your patient? Knowing the pharmacokinetic effects of medications—such as how long will the medication be absorbed and exert an effect on the body before it is eliminated—can have important implications for addressing your patient’s health needs. For this Discussion, think about the types of decisions you might make, with an understanding of pharmacokinetics, when prescribing medications for your patients. Reflect on how having a working knowledge of pharmacokinetics of medications is important in your role as an advanced practice nurse.

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