Describe the epigenetic impact on population health risks

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M5 Discussion Global cultures, environment & Epigenetics – Cynthia Payne
From Public Health & Community-based Nursing – 10752 NUR4636 202201No unread replies.No replies.
Objectives:
Define Consanguinity

Identify the global prevalence of consanguinity

Describe the epigenetic impact on population health risks

Discuss the cultural and ethical considerations of consanguineous unions. (Links to an external site.)

Note: Remember to check the calendar or syllabus’s course summary for the Response due date.
Background
As migrants move into western societies, long-held cultural beliefs arrive with them in their new communities and are often misunderstood. Consanguineous marriage is one such cultural practice. This social institution of marriage has been common across the globe throughout human history. Today, its rate varies significantly from one population to another, depending on religion, public attitude, culture, legislation, socio-economic condition, and geography.

Over the past 5-10 years, the mapping of the Genome has vastly increased our knowledge of consanguinity’s heredity (autosomal-recessive) risks. In western cultures, the rate of consanguinity is very low, compared to developing countries wherein certain ethnic groups, may account for more than 50% of marriages. (M. Islam. 2017. Consanguineous marriage in Oman: understanding the community awareness about congenital effects of and attitude towards consanguineous marriage. Annals of Human Biology, Vol 44(3), 273-286.)

Read the below 2019 review article on cultures that practice consanguineous unions:

Link to this article: 2019_ A review of the reproductive consequences of consanguinity Download Link to this article: 2019_ A review of the reproductive consequences of consanguinity

(FYI when reading a scholarly article read the sections in this order:
Title, abstract
Introduction
Discussion
View tables (to understand the findings and discussion)
Conclusion
Methods and findings (if you need to know more about the specific stats.)
To do:
Primary post: write a 350-word essay using APA discussion qualities (excellent organization, grammar, spelling, citations, introduction, body, and conclusion, 3 (or more) references).

Introduce and define Consanguinity (i.e., consanguineous marriages).
Discuss the epigenetic risks of consanguineous marriages.
Identify the global prevalence of consanguinity.
Discuss two (2) of the social/cultural beliefs that are predisposing or perpetuating factors for these consanguineous practices.
Discuss two factors that have reduced consanguinity in some populations.
Conclude with an insight you gained from this discussion.

________________________

Response post
Respond to one (1) classmate:

Choose one (1) of the below articles and briefly summarize its findings to extend the discussion with your classmate.
Describe how you would express cultural sensitivity when advising an at-risk couple for pre-conception genetic counseling.

Link here for the 2020 article The association between consanguineous marriage and offspring with congenital hearing loss Download The association between consanguineous marriage and offspring with congenital hearing loss

Link here for the 2016 article The Implications of Parental Consanguinity on the Care of Neonates.pdf Download The Implications of Parental Consanguinity on the Care of Neonates.pdf

Link here for the 2020 article: Epidemiology of Thalassemia in Gulf Cooperation Council Countries- A Systematic Review.pdf Download Epidemiology of Thalassemia in Gulf Cooperation Council Countries- A Systematic Review.pdf

Link here for 2017 article: 2017 Global distribution of consanguinity and their impact on complex diseases- Genetic disorders from an endogamous population.pdf Download 2017 Global distribution of consanguinity and their impact on complex diseases- Genetic disorders from an endogamous population.pdf

Word count 250 words or more.
Please help me to write the initial discussion. I will write the response post. thank you so much.

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