1.)Biochemistry Lab –
In 137 words or more using 2 references, please respond to the following question:
Enalapril is an anti-hypertension “pro-drug” (i.e., a drug precursor) that is inactive until the ethyl ester is hydrolyzed by esterases present in blood plasma. The active drug is the dicarboxylic acid (“enalaprilat”) that results from this hydrolysis reaction.
Enalapril is administered in pill form, but enalaprilat must be administered intravenously. Why do you suppose enalapril works as a pill, but enalaprilat does not?
2.)Biochemistry Lecture –
In 137 words or more using 2 references, please respond to the following question:
Why haven’t we found a cure yet for HIV and AIDS? A simple question, but a complex answer. Let me hear your thoughts, but please stay professional. You will find this to be likely be one of best discussions and it is usually the controversial ones that are, but sometimes these topics can impact us personally, so please be sensitive to that.
