The aim of the present study was to screen the genetic polymorphisms involved in Interleukin17A gene-Exon3 with AML in the Saudi population. the most important points that should cover in writing : 1- General info about gene and location of gene with picture from Gene cards for location. 2- Polymorphism and mutation specific in IL17A gene with Aml patients in Saudi Arabia and other countries and Some studies for polymorphism with IL17A gene with other hematology disease .