How many actin fibers are needed for the cells to deform a 50 μm2 area of the surface by 5%. Also, what is the minimum number of integrins needed to translate this force.

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You have seeded smooth muscle cells on a polymer scaffold with a modulus (that the cells “feel”) of 27 kPa. How many actin fibers are needed for the cells to deform a 50 μm2 area of the surface by 5%. Also, what is the minimum number of integrins needed to translate this force. Does the amount of force needed seem reasonable for the cells?

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