Explain why Breast cancer is the most prevalent cancer diagnosed in women in the United States excluding skin cancers and the second greatest cause of cancer death in women, following lung cancer. The American Cancer Society’s biennial update of the newest breast cancer statistics in the United States is presented. In 2021, women in the United States are predicted to be diagnosed with 281,550 new instances of invasive breast cancer and 49,290 new cases of non-invasive (in situ) breast cancer. Breast cancer is estimated to kill over 43,600 women in the United States in 2021. Since 2007, death rates for women under the age of 50 have remained stable, while death rates for women over the age of 50 have continued to decline. From 2013 to 2018, the total death rate from breast cancer fell by 1% every year (DeSantis et al., 2019). The USPSTF advises that clinicians administer risk-lowering drugs like tamoxifen, raloxifene, or aromatase inhibitors to women who are at high risk for breast cancer but have a low risk of side effects. The USPSTF has issued guidelines for breast cancer screening, risk assessment, genetic counseling, and BRCA genetic mutation testing. Low-dose x-rays of the breast are used in mammograms. Regular mammograms can aid in the early detection of breast cancer when treatment is most effective. Years before physical symptoms appear, mammography can detect breast abnormalities that could indicate cancer. The National Cancer Institute and the Centers for Disease Control and Prevention give information on measures to lower cancer risks, such as changes in lifestyle and food (USPSTF, 2019).